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Conclusion and recommendation Subject to negotiation of amendments to the Product Information document, the Delegate proposed to approve the registration of: · Palexia SR for the management tapentadol of moderate to severe chronic pain unresponsive to nonnarcotic analgesia .
Secondary efficacy parameters There was no significant difference across groups for WOMAC27 and Short Form (SF)-3628 27 Western Ontario and McMaster University tapentadol (WOMAC) questionnaire .
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001) when comparing oxycodone CR to tapentadol placebo . There was a AusPAR tapentadol Palexia SR Tapentadol CSL Ltd PM-2009-02489-3-1 Final 28 February 2011 Page 60 of 126 higher proportion of subjects with at least 30% improvement in the placebo group (p <0 .

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